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Filtered Search Results
eMolecules Pharmablock / 1-isobutylindole-3-carboxylic acid / 25mg / 783662743 / PBUD077 / 0.000 / 739365-10-7 / MFCD11155412 / 217.268 / C13H15NO2
Pharmablock / 1-isobutylindole-3-carboxylic acid / 25mg / 783662743 / PBUD077 / 0.000 / 739365-10-7 / MFCD11155412 / 217.268 / C13H15NO2
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Medchemexpress LLC (E)-2-(((5-bromothiophen-2-yl)methylene)amino)benzamide | 304456-62-0 | 98.0% | 309.18 | C12H9BrN2OS | 5MG
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BTYNB is a small-molecule research inhibitor of IMP1 (IGF2BP1) that disrupts IMP1 binding to c-Myc mRNA, resulting in reduced c-Myc expression and decreased proliferation in IMP1-positive cancer cell lines. The compound is supplied as a solid reagent in multiple sizes and as a 10 mM solution in DMSO for convenient stock preparation, and is reported with high purity for in vitro applications.
- Inhibits IMP1 binding to c-Myc mRNA with reported IC50 ≈ 5 μM.
- High reported purity suitable for in vitro research applications.
- Available in multiple solid pack sizes and a 10 mM solution format in DMSO.
- Soluble in DMSO for preparation of concentrated stock solutions.
- Used to study RNA-protein interactions and cancer cell proliferation.
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eMolecules AstaTech / 44-(PROPANE-13-DIYLBIS(OXY))BIS(5-METHOXY-2-NITROBENZOIC ACID) / 0.1g / 714092581 / C13785 / 95.000 / 140658-45-3 / MFCD15832842 / 466.355 / C19H18N2O12
AstaTech / 44-(PROPANE-13-DIYLBIS(OXY))BIS(5-METHOXY-2-NITROBENZOIC ACID) / 0.1g / 714092581 / C13785 / 95.000 / 140658-45-3 / MFCD15832842 / 466.355 / C19H18N2O12
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eMolecules Pharmablock / 5-ethoxypyridine-2-carboxylic acid / 25mg / 665626984 / PBT2928 / 0.000 / 98353-08-3 / MFCD13562922 / 167.164 / C8H9NO3
Pharmablock / 5-ethoxypyridine-2-carboxylic acid / 25mg / 665626984 / PBT2928 / 0.000 / 98353-08-3 / MFCD13562922 / 167.164 / C8H9NO3
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![eMolecules Medchem Express / PDE10-IN-5 / 5mg / 719836101 / HY-14550A / / 898562-99-7 / [null] / 460.460 / C26H19F3N4O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502474620.JPG-250.jpg)
eMolecules Medchem Express / PDE10-IN-5 / 5mg / 719836101 / HY-14550A / / 898562-99-7 / [null] / 460.460 / C26H19F3N4O
Medchem Express / PDE10-IN-5 / 5mg / 719836101 / HY-14550A / / 898562-99-7 / [null] / 460.460 / C26H19F3N4O
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Medchemexpress LLC C12H12N4O2S2 | 675104-49-1 | 99.8% | 308.38 | 100 MG
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DSHS00884 is a potent human papillomavirus E6 inhibitor with an IC50 of 10 μM. It stabilizes p53 levels in HPV-positive cells by blocking E6-mediated p53 degradation with an IC50 of 2.5-25 μM.
- Potent human papillomavirus E6 inhibitor
- Ic50 of 10 μM against human papillomavirus E6
- Stabilizes p53 levels in HPV-positive cells
- Blocks E6-mediated p53 degradation
- Ic50 of 2.5-25 μM for blocking E6-mediated p53 degradation
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Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 100 MG
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound is used for type 2 diabetes research.
- Inhibits human TXNIP promoter activity in INS-1 cells
- Reduces TXNIP mRNA and protein levels in INS-1 cells
- Inhibits Pol II binding to the E-box motif of the TXNIP promoter
- Lowers glucagon secretion in TC1-6 cells
- Inhibits glucagon-induced glucose output from primary hepatocytes
- Decreases glucagon secretion and blocks hepatic glucose output in mice
- Well tolerated in C57BL/6J mice
- Reverses obesity- and streptozotocin-induced diabetes and hepatic steatosis in mice
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Sigma Aldrich Fine Chemicals Biosciences Hypericum perforatum extract secondary reference standard | 84082-80-4 | 500MG
Hypericum perforatum extract secondary reference standard | 84082-80-4 | 500MG
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Medchemexpress LLC Diazinon | 333-41-5 | 99.3% | 100 MG
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Diazinon is an orally active, irreversible AChE inhibitor and insecticide that can be absorbed through the digestive system, skin, or respiratory tract. It inhibits AChE, leading to the accumulation of acetylcholine, which overstimulates ACh receptors and affects the nervous system. Diazinon also produces reactive oxygen species (ROS), inducing oxidative stress in various tissues. It is mainly used in agriculture as an insecticide and may affect human and animal health.
- Inhibits cell viability in BRL-3A cells and spleen mononuclear cells.
- Increases ROS generation and lipid peroxidation in BRL-3A cells.
- Induces cell cycle arrest at the G1 phase of SMC cells.
- Affects swimming behavior in Daphnia pulex.
- Causes a decrease in renal reduced glutathione in rats.
- Induces histopathological changes in the thymus and spleen of mice.
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eMolecules AstaTech / 2-CHLORO-6-(TRIFLUOROMETHOXY)ISONICOTINIC ACID / 0.1g / 722706844 / FD10674 / 95.000 / 1221171-97-6 / MFCD22571780 / 241.550 / C7H3ClF3NO3
AstaTech / 2-CHLORO-6-(TRIFLUOROMETHOXY)ISONICOTINIC ACID / 0.1g / 722706844 / FD10674 / 95.000 / 1221171-97-6 / MFCD22571780 / 241.550 / C7H3ClF3NO3
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eMolecules Ambeed / tert-Butyl 6-(hydroxymethyl)-34-dihydroisoquinoline-2(1H)-carboxylate / 50mg / 600835566 / A259109 / / 622867-52-1 / MFCD12408124 / 263.337 / C15H21NO3
Ambeed / tert-Butyl 6-(hydroxymethyl)-34-dihydroisoquinoline-2(1H)-carboxylate / 50mg / 600835566 / A259109 / / 622867-52-1 / MFCD12408124 / 263.337 / C15H21NO3
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules Ambeed / 2-(1H-Benzo[d]imidazol-2-yl)-45-dihydrooxazole / 100mg / 632172685 / A182707 / / 14483-99-9 / MFCD00460180 / 187.202 / C10H9N3O](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502441320.PNG-250.jpg)
eMolecules Ambeed / 2-(1H-Benzo[d]imidazol-2-yl)-45-dihydrooxazole / 100mg / 632172685 / A182707 / / 14483-99-9 / MFCD00460180 / 187.202 / C10H9N3O
Ambeed / 2-(1H-Benzo[d]imidazol-2-yl)-45-dihydrooxazole / 100mg / 632172685 / A182707 / / 14483-99-9 / MFCD00460180 / 187.202 / C10H9N3O
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules ChemScene / 6-Methoxy-2-methylquinoline-3-carboxylic acid / 100mg / 686142685 / CS-0220645 / 0.000 / 88752-76-5 / MFCD00841563 / 217.224 / C12H11NO3
ChemScene / 6-Methoxy-2-methylquinoline-3-carboxylic acid / 100mg / 686142685 / CS-0220645 / 0.000 / 88752-76-5 / MFCD00841563 / 217.224 / C12H11NO3
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules Medchem Express / Fmoc-Ala-OH-3-13C / 50mg / 721611346 / HY-W009204S3 / / 201489-21-6 / MFCD00209684 / 312.329 / C18H17NO4
Medchem Express / Fmoc-Ala-OH-3-13C / 50mg / 721611346 / HY-W009204S3 / / 201489-21-6 / MFCD00209684 / 312.329 / C18H17NO4
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules AstaTech / 3-CHLOROPHTHALONITRILE / 0.25g / 718056784 / CL8193 / 95.000 / 76241-79-7 / MFCD19689405 / 162.580 / C8H3ClN2
AstaTech / 3-CHLOROPHTHALONITRILE / 0.25g / 718056784 / CL8193 / 95.000 / 76241-79-7 / MFCD19689405 / 162.580 / C8H3ClN2
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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